| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-U receptor 1 |
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| Ligand | BDBM50238706 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1664053 (CHEMBL4013734) |
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| EC50 | 2.5±n/a nM |
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| Citation |  Kanematsu-Yamaki, Y; Nishizawa, N; Kaisho, T; Nagai, H; Mochida, T; Asakawa, T; Inooka, H; Dote, K; Fujita, H; Matsumiya, K; Hirabayashi, H; Sakamoto, J; Ohtaki, T; Takekawa, S; Asami, T Potent Body Weight-Lowering Effect of a Neuromedin U Receptor 2-selective PEGylated Peptide. J Med Chem60:6089-6097 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-U receptor 1 |
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| Name: | Neuromedin-U receptor 1 |
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| Synonyms: | G-protein coupled receptor 66 | G-protein coupled receptor FM-3 | Gpr66 | NMU-R1 | NMUR1_MOUSE | Nmur1 |
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| Type: | n/a |
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| Mol. Mass.: | 47951.94 |
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| Organism: | Mus musculus |
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| Description: | n/a |
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| Residue: | 428 |
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| Sequence: | MTPPCLNCSIFPGALSPNASRSPLVCNISEFKWPYQPEDLNLTDEALRLKYLGPQQMKQF
VPICVTYLLIFVVGTLGNGLTCTVILRNKTMRTPTNFYLFSLAVSDMLVLLVGLPLELYE
MQQNYPFQLGASACYFRILLLETVCLASVLNVTALSVERYVAVVRPLQAKSVMTRAHVRR
MVGAIWVLATLFSLPNTSLHGLSQLTVPCRGPVPDSAICSLVGPMDFYKLVVLTTALLFF
CLPMVTISVLYLLIGLRLRRERMLLQVEVKGRKTAATQETSHRRIQLQDRGRRQVTKMLF
ALVVVFGICWAPFHADRIMWSLVYGHSTEGLHLAYQCVHIASGIFFYLGSAANPVLYSLM
STRFRETFLQALGLGTQCCHRRQPYHGSHNHIRLTTGSTLCDVGHRNSRDEPLAVNEDPG
CQQETDPS
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| BDBM50238706 |
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| n/a |
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| Name | BDBM50238706 |
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| Synonyms: | CHEMBL4099780 |
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| Type | Small organic molecule |
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| Emp. Form. | C63H91N17O11 |
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| Mol. Mass. | 1262.5039 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@H](Cc1ccc2ccccc2c1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CCCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N(C)[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(N)=O |r| |
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| Structure | 
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