| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
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| Ligand | BDBM50227141 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1664812 (CHEMBL4014608) |
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| IC50 | 240±n/a nM |
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| Citation |  Proschak, E; Heitel, P; Kalinowsky, L; Merk, D Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery. J Med Chem60:5235-5266 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 1 |
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| Name: | Cysteinyl leukotriene receptor 1 |
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| Synonyms: | CLTR1_CAVPO | CYSLTR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39007.58 |
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| Organism: | GUINEA PIG |
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| Description: | Leukotriene D4 0 GUINEA PIG::Q2NNR5 |
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| Residue: | 340 |
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| Sequence: | MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSA
FQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAM
SFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPP
QDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIV
VTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFF
SGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
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| BDBM50227141 |
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| n/a |
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| Name | BDBM50227141 |
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| Synonyms: | CHEMBL174483 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23NO5 |
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| Mol. Mass. | 405.4431 |
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| SMILES | CCCCCc1ccc(\C=C\C(=O)Nc2cccc3c2oc(cc3=O)C(O)=O)cc1 |
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| Structure | 
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