| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteinyl leukotriene receptor 1 |
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| Ligand | BDBM50239015 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1664816 (CHEMBL4014612) |
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| IC50 | 2.3±n/a nM |
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| Citation |  Proschak, E; Heitel, P; Kalinowsky, L; Merk, D Opportunities and Challenges for Fatty Acid Mimetics in Drug Discovery. J Med Chem60:5235-5266 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteinyl leukotriene receptor 1 |
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| Name: | Cysteinyl leukotriene receptor 1 |
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| Synonyms: | CLTR1_HUMAN | CYSLT1 | CYSLTR1 | Cysteinyl leukotriene D4 receptor | Cysteinyl leukotriene receptor | Cysteinyl leukotriene receptor 1 | HG55 | HMTMF81 | LTD4 receptor | Leukotriene Cysteinyl 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 38565.16 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Leukotriene Cysteinyl 1 CYSLTR1 HUMAN::Q9Y271 |
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| Residue: | 337 |
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| Sequence: | MDETGNLTVSSATCHDTIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLIKTYHKKSAFQV
YMINLAVADLLCVCTLPLRVVYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFF
RCIAIVFPVQNINLVTQKKARFVCVGIWIFVILTSSPFLMAKPQKDEKNNTKCFEPPQDN
QTKNHVLVLHYVSLFVGFIIPFVIIIVCYTMIILTLLKKSMKKNLSSHKKAIGMIMVVTA
AFLVSFMPYHIQRTIHLHFLHNETKPCDSVLRMQKSVVITLSLAASNCCFDPLLYFFSGG
NFRKRLSTFRKHSLSSVTYVPRKKASLPEKGEEICKV
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| BDBM50239015 |
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| n/a |
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| Name | BDBM50239015 |
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| Synonyms: | CHEBI:6993 | MK-476 | Montelukast Sodium | Singulair |
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| Type | Small organic molecule |
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| Emp. Form. | C35H35ClNNaO3S |
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| Mol. Mass. | 608.165 |
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| SMILES | [Na+].CC(C)(O)c1ccccc1CC[C@@H](SCC1(CC([O-])=O)CC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 |r| |
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| Structure | 
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