| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1B |
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| Ligand | BDBM85165 |
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| Substrate/Competitor | n/a |
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| Ki | 794.32±n/a nM |
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| Comments | PDSP_416 |
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| Citation |  Price, GW; Burton, MJ; Collin, LJ; Duckworth, M; Gaster, L; Göthert, M; Jones, BJ; Roberts, C; Watson, JM; Middlemiss, DN SB-216641 and BRL-15572--compounds to pharmacologically discriminate h5-HT1B and h5-HT1D receptors. Naunyn Schmiedebergs Arch Pharmacol356:312-20 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 1B |
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| Name: | 5-hydroxytryptamine receptor 1B |
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| Synonyms: | 5-HT-1B | 5-HT-1D-beta | 5-HT1B | 5-hydroxytryptamine receptor 1B (5-HT1B) | 5HT1B_HUMAN | HTR1B | HTR1DB | S12 | Serotonin (5-HT) receptor | Serotonin 1D beta receptor | Serotonin Receptor 1B |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 43579.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Receptor binding assays were performed using human clone stably expressed in CHO cells |
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| Residue: | 390 |
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| Sequence: | MEEPGAQCAPPPPAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALIT
LATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQV
VCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISI
SLPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRIL
KQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLE
KKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYL
NSLINPIIYTMSNEDFKQAFHKLIRFKCTS
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| BDBM85165 |
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| n/a |
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| Name | BDBM85165 |
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| Synonyms: | 4-(3-CHLOROPHENYL)-ALPHA-(DIPHENYLMETHYL)-1-PIPERAZINEETHANOL HYDROCHLORIDE | BRL 15572 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H27ClN2O |
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| Mol. Mass. | 406.948 |
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| SMILES | OC(CN1CCN(CC1)c1cccc(Cl)c1)C(c1ccccc1)c1ccccc1 |
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| Structure | 
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