| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-9 |
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| Ligand | BDBM50100712 |
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| Substrate/Competitor | n/a |
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| Ki | 6.5±n/a nM |
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| Comments | PDSP_982 |
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| Citation |  Mukhin, AG; Gündisch, D; Horti, AG; Koren, AO; Tamagnan, G; Kimes, AS; Chambers, J; Vaupel, DB; King, SL; Picciotto, MR; Innis, RB; London, ED 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors. Mol Pharmacol57:642-9 (2000) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Neuronal acetylcholine receptor subunit alpha-9 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-9 |
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| Synonyms: | ACHA9_RAT | Acra9 | Cholinergic, Nicotinic Muscle | Chrna9 | NACHR alpha 9 | Neuronal acetylcholine receptor subunit alpha-9 | Nicotinic acetylcholine receptor subunit alpha 9 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 54522.69 |
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| Organism: | RAT |
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| Description: | Cholinergic, Nicotinic Muscle 0 RAT::P43144 |
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| Residue: | 479 |
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| Sequence: | MNRPHSCLSFCWMYFAASGIRAVETANGKYAQKLFSDLFEDYSSALRPVEDTDAVLNVTL
QVTLSQIKDMDERNQILTAYLWIRQTWHDAYLTWDRDQYDRLDSIRIPSDLVWRPDIVLY
NKADDESSEPVNTNVVLRYDGLITWDSPAITKSSCVVDVTYFPFDSQQCNLTFGSWTYNG
NQVDIFNALDSGDLSDFIEDVEWEVHGMPAVKNVISYGCCSEPYPDVTFTLLLKRRSSFY
IVNLLIPCVLISFLAPLSFYLPAASGEKVSLGVTILLAMTVFQLMVAEIMPASENVPLIG
KYYIATMALITASTALTIMVMNIHFCGAEARPVPHWAKVVILKYMSRILFVYDVGESCLS
PRHSQEPEQVTKVYSKLPESNLKTSRNKDLSRKKEVRKLLKNDLGYQGGIPQNTDSYCAR
YEALTKNIEYIAKCLKDHKATNSKGSEWKKVAKVIDRFFMWIFFAMVFVMTVLIIARAD
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| BDBM50100712 |
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| n/a |
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| Name | BDBM50100712 |
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| Synonyms: | 2-(6-Iodo-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | CHEMBL54586 | Epibatidine-I,(+/-) | IPH |
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| Type | Small organic molecule |
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| Emp. Form. | C11H13IN2 |
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| Mol. Mass. | 300.1388 |
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| SMILES | Ic1ccc(cn1)C1CC2CCC1N2 |THB:4:7:13:11.10| |
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| Structure | 
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