| Reaction Details |
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 | Report a problem with these data |
| Target | Prostaglandin-H2 D-isomerase |
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| Ligand | BDBM50060462 |
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| Substrate/Competitor | n/a |
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| Ki | 1.6±n/a nM |
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| Comments | PDSP_2287 |
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| Citation |  Arimura, A; Yasui, K; Kishino, J; Asanuma, F; Hasegawa, H; Kakudo, S; Ohtani, M; Arita, H Prevention of allergic inflammation by a novel prostaglandin receptor antagonist, S-5751. J Pharmacol Exp Ther298:411-9 (2001) [PubMed] |
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| More Info.: | Get all data from this article |
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| Prostaglandin-H2 D-isomerase |
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| Name: | Prostaglandin-H2 D-isomerase |
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| Synonyms: | PDS | PGD2 | PTGDS | PTGDS_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 21031.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PGD2 0 HUMAN::P41222 |
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| Residue: | 190 |
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| Sequence: | MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKA
ALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSV
VETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFL
PQTDKCMTEQ
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| BDBM50060462 |
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| n/a |
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| Name | BDBM50060462 |
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| Synonyms: | (Z)-7-{(1R,2R,3S,5S)-2-[(5-Hydroxy-benzo[b]thiophene-3-carbonyl)-amino]-6,6-dimethyl-bicyclo[3.1.1]hept-3-yl}-hept-5-enoic acid | CHEMBL116837 | S-5751 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H31NO4S |
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| Mol. Mass. | 441.583 |
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| SMILES | CC1(C)[C@@H]2C[C@H]1[C@H](NC(=O)c1csc3ccc(O)cc13)[C@@H](C\C=C/CCCC(O)=O)C2 |
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| Structure | 
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