| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM84637 |
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| Substrate/Competitor | n/a |
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| Ki | 1000±n/a nM |
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| Comments | PDSP_1575 |
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| Citation |  Mottola, DM; Kilts, JD; Lewis, MM; Connery, HS; Walker, QD; Jones, SR; Booth, RG; Hyslop, DK; Piercey, M; Wightman, RM; Lawler, CP; Nichols, DE; Mailman, RB Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase. J Pharmacol Exp Ther301:1166-78 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM84637 |
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| n/a |
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| Name | BDBM84637 |
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| Synonyms: | CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPIROLE | Quinpirole,(-) | US9359372, Quinpirole |
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| Type | Small organic molecule |
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| Emp. Form. | C13H21N3 |
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| Mol. Mass. | 219.3259 |
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| SMILES | CCCN1CCC[C@@H]2Cc3[nH]ncc3C[C@@H]12 |r| |
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| Structure | 
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