| Reaction Details |
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 | Report a problem with these data |
| Target | Polyadenylate-binding protein 1 |
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| Ligand | BDBM87599 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay |
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| IC50 | >66000±n/a nM |
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| Citation |  PubChem, PC Dose-response confirmation of microRNA-mediated mRNA deadenylation inhibitors by fluoresence polarization assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Polyadenylate-binding protein 1 |
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| Name: | Polyadenylate-binding protein 1 |
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| Synonyms: | PAB1 | PABP | PABP1 | PABP1_HUMAN | PABPC1 | PABPC2 | poly(A) binding protein, cytoplasmic 1 | polyadenylate-binding protein 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 70694.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_46367787 |
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| Residue: | 636 |
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| Sequence: | MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQ
QPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFS
AFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKERE
AELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFER
HEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKN
LDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVAT
KPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRA
AYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQ
RVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQ
GQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESP
ESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
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| BDBM87599 |
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| n/a |
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| Name | BDBM87599 |
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| Synonyms: | 1-(4-Methyl-piperidin-1-yl)-2-(4-pyridin-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl)-ethanone | 1-(4-methyl-1-piperidinyl)-2-[[4-(2-pyridinyl)-1,2,4-triazol-3-yl]thio]ethanone | 1-(4-methylpiperidin-1-yl)-2-[(4-pyridin-2-yl-1,2,4-triazol-3-yl)sulfanyl]ethanone | 1-(4-methylpiperidino)-2-[[4-(2-pyridyl)-1,2,4-triazol-3-yl]thio]ethanone | MLS000074873 | SMR000002005 | cid_648833 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H19N5OS |
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| Mol. Mass. | 317.409 |
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| SMILES | CC1CCN(CC1)C(=O)CSc1nncn1-c1ccccn1 |
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| Structure | 
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