Reaction Details |
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Target | Dual specificity protein phosphatase 3 |
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Ligand | BDBM34462 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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IC50 | 339±n/a nM |
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Citation | PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity protein phosphatase 3 |
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Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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BDBM34462 |
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n/a |
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Name | BDBM34462 |
Synonyms: | (3,4-dichlorophenyl)-[4-(2-hydroxyethyl)-1-piperazinyl]methanethione | (3,4-dichlorophenyl)-[4-(2-hydroxyethyl)piperazin-1-yl]methanethione | (3,4-dichlorophenyl)-[4-(2-hydroxyethyl)piperazino]methanethione | 2-{4-[(3,4-dichlorophenyl)carbonothioyl]-1-piperazinyl}ethanol | MLS000049575 | SMR000076115 | cid_963027 |
Type | Small organic molecule |
Emp. Form. | C13H16Cl2N2OS |
Mol. Mass. | 319.25 |
SMILES | OCCN1CCN(CC1)C(=S)c1ccc(Cl)c(Cl)c1 |
Structure |
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