Reaction Details |
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Target | Dual specificity protein phosphatase 3 |
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Ligand | BDBM88723 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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IC50 | 719±n/a nM |
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Citation | PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity protein phosphatase 3 |
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Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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BDBM88723 |
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n/a |
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Name | BDBM88723 |
Synonyms: | (4-benzylpiperazin-1-yl)-(4-bromophenyl)methanethione | (4-benzylpiperazino)-(4-bromophenyl)methanethione | (4-bromophenyl)-[4-(phenylmethyl)-1-piperazinyl]methanethione | (4-bromophenyl)-[4-(phenylmethyl)piperazin-1-yl]methanethione | 1-benzyl-4-[(4-bromophenyl)carbonothioyl]piperazine | MLS000576820 | SMR000198100 | cid_2185493 |
Type | Small organic molecule |
Emp. Form. | C18H19BrN2S |
Mol. Mass. | 375.326 |
SMILES | Brc1ccc(cc1)C(=S)N1CCN(Cc2ccccc2)CC1 |
Structure |
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