Reaction Details |
![](/images/Email.png) | Report a problem with these data |
Target | Dual specificity protein phosphatase 3 |
---|
Ligand | BDBM88764 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
---|
IC50 | 1120±n/a nM |
---|
Citation | PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Dual specificity protein phosphatase 3 |
---|
Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
|
|
|
BDBM88764 |
---|
n/a |
---|
Name | BDBM88764 |
Synonyms: | 1-(3-chloranyl-4-methoxy-phenyl)-3-(3-pyrrolidin-1-ylpropyl)thiourea | 1-(3-chloro-4-methoxy-phenyl)-3-(3-pyrrolidinopropyl)thiourea | 1-(3-chloro-4-methoxyphenyl)-3-(3-pyrrolidin-1-ylpropyl)thiourea | 1-(3-chloro-4-methoxyphenyl)-3-[3-(1-pyrrolidinyl)propyl]thiourea | MLS000730543 | N-(3-chloro-4-methoxyphenyl)-N'-(3-pyrrolidin-1-ylpropyl)thiourea | SMR000308819 | cid_16193058 |
Type | Small organic molecule |
Emp. Form. | C15H22ClN3OS |
Mol. Mass. | 327.873 |
SMILES | COc1ccc(NC(=S)NCCCN2CCCC2)cc1Cl |
Structure |
|