Reaction Details |
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Target | Dual specificity protein phosphatase 3 |
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Ligand | BDBM61325 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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IC50 | 509±n/a nM |
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Citation | PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity protein phosphatase 3 |
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Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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BDBM61325 |
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n/a |
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Name | BDBM61325 |
Synonyms: | 1-N,3-N-bis(2-hydroxy-5-nitrophenyl)benzene-1,3-dicarboxamide | MLS001008494 | N,N'-bis(2-hydroxy-5-nitrophenyl)isophthalamide | N,N'-bis(2-hydroxy-5-nitro-phenyl)isophthalamide | N1,N3-bis(2-hydroxy-5-nitrophenyl)benzene-1,3-dicarboxamide | N1,N3-bis(5-nitro-2-oxidanyl-phenyl)benzene-1,3-dicarboxamide | SMR000495849 | cid_3823676 |
Type | Small organic molecule |
Emp. Form. | C20H14N4O8 |
Mol. Mass. | 438.3472 |
SMILES | Oc1ccc(cc1NC(=O)c1cccc(c1)C(=O)Nc1cc(ccc1O)[N+]([O-])=O)[N+]([O-])=O |
Structure |
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