Reaction Details |
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Target | Dual specificity protein phosphatase 3 |
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Ligand | BDBM83199 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay |
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IC50 | 544±n/a nM |
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Citation | PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Dual specificity protein phosphatase 3 |
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Name: | Dual specificity protein phosphatase 3 |
Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
Type: | Hydrolase |
Mol. Mass.: | 20480.58 |
Organism: | Homo sapiens (Human) |
Description: | n/a |
Residue: | 185 |
Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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BDBM83199 |
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n/a |
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Name | BDBM83199 |
Synonyms: | 2-[7-(dihydroxymethylene)-5,6-diketo-cyclohepta-1,3-dien-1-yl]acetic acid | 2-[7-(dihydroxymethylidene)-5,6-dioxo-1-cyclohepta-1,3-dienyl]acetic acid | 2-[7-(dihydroxymethylidene)-5,6-dioxocyclohepta-1,3-dien-1-yl]acetic acid | 2-[7-[bis(oxidanyl)methylidene]-5,6-bis(oxidanylidene)cyclohepta-1,3-dien-1-yl]ethanoic acid | 7-(carboxymethyl)-2-hydroxy-3-keto-cyclohepta-1,4,6-triene-1-carboxylic acid | MLS002703575 | SMR001570292 | cid_5380595 |
Type | Small organic molecule |
Emp. Form. | C10H8O6 |
Mol. Mass. | 224.1669 |
SMILES | OC(=O)Cc1cccc(=O)c(O)c1C(O)=O |
Structure |
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