Reaction Details |
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Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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Ligand | BDBM78075 |
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Substrate/Competitor | n/a |
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Meas. Tech. | SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. |
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IC50 | 2570±n/a nM |
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Citation | PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Mitochondrial import inner membrane translocase subunit TIM10 |
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Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 10303.50 |
Organism: | Saccharomyces cerevisiae S288c |
Description: | gi_285809906 |
Residue: | 93 |
Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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BDBM78075 |
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n/a |
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Name | BDBM78075 |
Synonyms: | 2-(4-methylphenoxy)acetic acid [(Z)-[1-amino-2-(4-chlorophenyl)ethylidene]amino] ester | MLS000556012 | SMR000147529 | [(Z)-[1-amino-2-(4-chlorophenyl)ethylidene]amino] 2-(4-methylphenoxy)acetate | [(Z)-[1-azanyl-2-(4-chlorophenyl)ethylidene]amino] 2-(4-methylphenoxy)ethanoate | cid_5919570 |
Type | Small organic molecule |
Emp. Form. | C17H17ClN2O3 |
Mol. Mass. | 332.781 |
SMILES | Cc1ccc(OCC(=O)ONC(=N)Cc2ccc(Cl)cc2)cc1 |
Structure |
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