| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Ligand | BDBM77793 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. |
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| IC50 | 14100±n/a nM |
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| Citation |  PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM10 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 10303.50 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285809906 |
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| Residue: | 93 |
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| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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| BDBM77793 |
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| n/a |
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| Name | BDBM77793 |
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| Synonyms: | (2-Pyridin-3-yl-quinazolin-4-yl)-p-tolyl-amine | MLS001029627 | N-(4-methylphenyl)-2-(3-pyridinyl)-4-quinazolinamine | N-(4-methylphenyl)-2-pyridin-3-yl-quinazolin-4-amine | N-(4-methylphenyl)-2-pyridin-3-ylquinazolin-4-amine | SMR000426957 | cid_921932 | p-tolyl-[2-(3-pyridyl)quinazolin-4-yl]amine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N4 |
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| Mol. Mass. | 312.3678 |
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| SMILES | Cc1ccc(Nc2nc(nc3ccccc23)-c2cccnc2)cc1 |
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| Structure | 
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