| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM90084 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex |
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| EC50 | >53000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM90084 |
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| n/a |
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| Name | BDBM90084 |
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| Synonyms: | 2-Acetylamino-N-(3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-3-p-tolyl-propionamide | 2-acetamido-3-(4-methylphenyl)-N-[1-(3-nitro-2-pyridinyl)-4-piperidinyl]propanamide | 2-acetamido-3-(4-methylphenyl)-N-[1-(3-nitropyridin-2-yl)piperidin-4-yl]propanamide | 2-acetamido-N-[1-(3-nitro-2-pyridyl)-4-piperidyl]-3-(p-tolyl)propionamide | MLS000559312 | SMR000173735 | cid_3232421 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N5O4 |
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| Mol. Mass. | 425.4809 |
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| SMILES | CC(=O)NC(Cc1ccc(C)cc1)C(=O)NC1CCN(CC1)c1ncccc1[N+]([O-])=O |
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| Structure | 
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