Ki Summary

Reaction Details

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Target

Tyrosine-protein phosphatase non-receptor type 5

Ligand

BDBM47086

Substrate/Competitor

n/a

Meas. Tech.

Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.

IC50

8340±n/a nM

Citation

PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Tyrosine-protein phosphatase non-receptor type 5

Name:

Tyrosine-protein phosphatase non-receptor type 5

Synonyms:

PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

63510.68

Organism:

Homo sapiens (Human)

Description:

gi_90652859

Residue:

565

Sequence:

MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE

BDBM47086

n/a

Name

BDBM47086

Synonyms:

2-(3-methylanilino)-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one | 2-(m-toluidino)-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one | 2-[(3-methylphenyl)amino]-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one | 2-[(3-methylphenyl)amino]-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one | MLS000095263 | SMR000030817 | cid_3238944

Type

Small organic molecule

Emp. Form.

C16H12N4OS

Mol. Mass.

308.358

SMILES

Cc1cccc(Nc2nn3c(nc4ccccc4c3=O)s2)c1

Structure