Ki Summary

Reaction Details

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Target

Tyrosine-protein phosphatase non-receptor type 5

Ligand

BDBM88772

Substrate/Competitor

n/a

Meas. Tech.

Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.

IC50

32000±n/a nM

Citation

PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay(2012)[AID]

More Info.:

Get all data from this article, Assay Method

Tyrosine-protein phosphatase non-receptor type 5

Name:

Tyrosine-protein phosphatase non-receptor type 5

Synonyms:

PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a

Type:

Enzyme Catalytic Domain

Mol. Mass.:

63510.68

Organism:

Homo sapiens (Human)

Description:

gi_90652859

Residue:

565

Sequence:

MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE

BDBM88772

n/a

Name

BDBM88772

Synonyms:

(4-benzylpiperazin-1-yl)-(5-methylthiophen-2-yl)methanethione | (4-benzylpiperazino)-(5-methyl-2-thienyl)methanethione | (5-methyl-2-thiophenyl)-[4-(phenylmethyl)-1-piperazinyl]methanethione | (5-methylthiophen-2-yl)-[4-(phenylmethyl)piperazin-1-yl]methanethione | MLS000771422 | SMR000376801 | cid_2455027

Type

Small organic molecule

Emp. Form.

C17H20N2S2

Mol. Mass.

316.484

SMILES

Cc1ccc(s1)C(=S)N1CCN(Cc2ccccc2)CC1

Structure