Reaction Details |
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Target | Tyrosine-protein phosphatase non-receptor type 5 |
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Ligand | BDBM88772 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. |
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IC50 | 32000±n/a nM |
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Citation | PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Tyrosine-protein phosphatase non-receptor type 5 |
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Name: | Tyrosine-protein phosphatase non-receptor type 5 |
Synonyms: | PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 63510.68 |
Organism: | Homo sapiens (Human) |
Description: | gi_90652859 |
Residue: | 565 |
Sequence: | MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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BDBM88772 |
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n/a |
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Name | BDBM88772 |
Synonyms: | (4-benzylpiperazin-1-yl)-(5-methylthiophen-2-yl)methanethione | (4-benzylpiperazino)-(5-methyl-2-thienyl)methanethione | (5-methyl-2-thiophenyl)-[4-(phenylmethyl)-1-piperazinyl]methanethione | (5-methylthiophen-2-yl)-[4-(phenylmethyl)piperazin-1-yl]methanethione | MLS000771422 | SMR000376801 | cid_2455027 |
Type | Small organic molecule |
Emp. Form. | C17H20N2S2 |
Mol. Mass. | 316.484 |
SMILES | Cc1ccc(s1)C(=S)N1CCN(Cc2ccccc2)CC1 |
Structure |
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