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TargetTyrosine-protein phosphatase non-receptor type 5
LigandBDBM88772
Substrate/Competitorn/a
Meas. Tech.Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
IC50 32000±n/a nM
Citation PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 5
Name:Tyrosine-protein phosphatase non-receptor type 5
Synonyms:PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:Enzyme Catalytic Domain
Mol. Mass.:63510.68
Organism:Homo sapiens (Human)
Description:gi_90652859
Residue:565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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  Blast E-value cutoff:
BDBM88772
n/a
NameBDBM88772
Synonyms:(4-benzylpiperazin-1-yl)-(5-methylthiophen-2-yl)methanethione | (4-benzylpiperazino)-(5-methyl-2-thienyl)methanethione | (5-methyl-2-thiophenyl)-[4-(phenylmethyl)-1-piperazinyl]methanethione | (5-methylthiophen-2-yl)-[4-(phenylmethyl)piperazin-1-yl]methanethione | MLS000771422 | SMR000376801 | cid_2455027
TypeSmall organic molecule
Emp. Form.C17H20N2S2
Mol. Mass.316.484
SMILESCc1ccc(s1)C(=S)N1CCN(Cc2ccccc2)CC1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: