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TargetTyrosine-protein phosphatase non-receptor type 5
LigandBDBM88807
Substrate/Competitorn/a
Meas. Tech.Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
IC50 32500±n/a nM
Citation PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article,  Assay Method
 
Tyrosine-protein phosphatase non-receptor type 5
Name:Tyrosine-protein phosphatase non-receptor type 5
Synonyms:PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:Enzyme Catalytic Domain
Mol. Mass.:63510.68
Organism:Homo sapiens (Human)
Description:gi_90652859
Residue:565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPP
PPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLV
SSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPED
RRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQ
ERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLL
QAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIR
GYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYD
GVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEE
AAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQ
TCEQYQFVHHVMSLYEKQLSHQSPE
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  Blast E-value cutoff:
BDBM88807
n/a
NameBDBM88807
Synonyms:1,3-bis[[(E)-(6-ketocyclohexa-2,4-dien-1-ylidene)methyl]amino]urea | 1,3-bis[[(E)-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)methyl]amino]urea | 1,3-bis[[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]amino]urea | 1,3-bis[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]urea | MLS002667171 | SMR001556943 | cid_5372293
TypeSmall organic molecule
Emp. Form.C15H14N4O3
Mol. Mass.298.2967
SMILESOc1ccccc1C=NNC(=O)NN=Cc1ccccc1O |w:8.9,13.13|
Structure
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