| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Ligand | BDBM92279 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ITC |
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| pH | 7±n/a |
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| Temperature | 298.15±n/a K |
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| Kd | 2250±n/a nM |
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| Citation |  CSARdock, CD LPXC in CSAR_FULL_RELEASE_3JULY2012 CSAR1:0 (2012) |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Name: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Synonyms: | LPXC_AQUAE | UDP-3-O-Acyl-GlcNAc Deacetylase (LpxC) | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase | envA | lpxC | zinc deacetylase LpxC |
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| Type: | Hydrolase |
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| Mol. Mass.: | 32146.02 |
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| Organism: | Aquifex aeolicus |
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| Description: | The enzyme was stripped of all metal ions by dialysis against 1.0 mM EDTA in buffer at room temperature. The EDTA was then removed by extensive dialysis against EDTA-free buffer and the enzyme was reconstituted to a 1:1 Zn2+ to LpxC ratio by the addition of ZnSO4. |
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| Residue: | 282 |
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| Sequence: | MGLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHST
DLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNRE
IDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTF
CFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGS
PVKGKFYSFRGGHSLNVKLVKELAKKQKLTRDLPHLPSVQAL
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| BDBM92279 |
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| n/a |
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| Name | BDBM92279 |
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| Synonyms: | CS272 |
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| Type | n/a |
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| Emp. Form. | C12H10FN3O3 |
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| Mol. Mass. | 263.2245 |
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| SMILES | ONC(=O)[C@H]1COC(=N1)c1cc2cc(F)ccc2[nH]1 |c:7| |
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| Structure | 
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