| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM64783 |
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| Substrate/Competitor | n/a |
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| IC50 | 2320±167 nM |
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| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM64783 |
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| n/a |
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| Name | BDBM64783 |
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| Synonyms: | 1-(2,1,3-benzothiadiazol-5-yl)-3-(4-ethoxyphenyl)thiourea | 1-piazthiol-5-yl-3-p-phenetyl-thiourea | MLS000576242 | N-2,1,3-benzothiadiazol-5-yl-N'-(4-ethoxyphenyl)thiourea | SMR000197073 | cid_804043 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4OS2 |
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| Mol. Mass. | 330.428 |
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| SMILES | CCOc1ccc(NC(=S)Nc2ccc3nsnc3c2)cc1 |
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| Structure | 
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