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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Sentrin-specific protease 8 | ||
| Ligand | BDBM93579 | ||
| Substrate/Competitor | n/a | ||
| IC50 | 1210±91 nM | ||
| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] | ||
| More Info.: | Get all data from this article | ||
| Sentrin-specific protease 8 | |||
| Name: | Sentrin-specific protease 8 | ||
| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 24104.52 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_262118306 | ||
| Residue: | 212 | ||
| Sequence: |
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| BDBM93579 | |||
| n/a | |||
| Name | BDBM93579 | ||
| Synonyms: | (1S,2S,3S,10bR)-3-benzoyl-2-(4-fluorobenzoyl)spiro[3,10b-dihydro-2H-pyrrol[2,1-a]isoquinoline-1,3'-indoline]-2'-one | (2'S,3S,3'S,10'bR)-2'-(4-fluorophenyl)carbonyl-3'-(phenylcarbonyl)spiro[1H-indole-3,1'-3,10b-dihydro-2H-pyrrolo[2,1-a]isoquinoline]-2-one | (2'S,3S,3'S,10'bR)-3'-benzoyl-2'-(4-fluorobenzoyl)spiro[1H-indole-3,1'-3,10b-dihydro-2H-pyrrolo[2,1-a]isoquinoline]-2-one | (2'S,3S,3'S,10'bR)-3'-benzoyl-2'-[(4-fluorophenyl)-oxomethyl]-2-spiro[1H-indole-3,1'-3,10b-dihydro-2H-pyrrolo[2,1-a]isoquinoline]one | MLS000590115 | SMR000219322 | cid_15944915 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C33H23FN2O3 | ||
| Mol. Mass. | 514.5457 | ||
| SMILES | Fc1ccc(cc1)C(=O)[C@@H]1[C@H](N2C=Cc3ccccc3[C@@H]2[C@]11C(=O)Nc2ccccc12)C(=O)c1ccccc1 |c:13| | ||
| Structure | 
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