Reaction Details |
![](/images/Email.png) | Report a problem with these data |
Target | Sentrin-specific protease 8 |
---|
Ligand | BDBM48009 |
---|
Substrate/Competitor | n/a |
---|
IC50 | 985±125 nM |
---|
Citation | PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
---|
More Info.: | Get all data from this article |
---|
|
Sentrin-specific protease 8 |
---|
Name: | Sentrin-specific protease 8 |
Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 24104.52 |
Organism: | Homo sapiens (Human) |
Description: | gi_262118306 |
Residue: | 212 |
Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
|
|
|
BDBM48009 |
---|
n/a |
---|
Name | BDBM48009 |
Synonyms: | 8-fluoranylindolo[2,1-b]quinazoline-6,12-dione | 8-fluoroindolo[2,1-b]quinazoline-6,12-dione | 8-fluoroindolo[2,1-b]quinazoline-6,12-quinone | MLS001216278 | SMR000544298 | US10669273, Compound 5c | cid_478574 |
Type | Small organic molecule |
Emp. Form. | C15H7FN2O2 |
Mol. Mass. | 266.2267 |
SMILES | Fc1ccc-2c(c1)C(=O)c1nc3ccccc3c(=O)n-21 |
Structure |
|