| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM70989 |
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| Substrate/Competitor | n/a |
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| IC50 | 2980±340 nM |
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| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM70989 |
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| n/a |
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| Name | BDBM70989 |
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| Synonyms: | (7-morpholinobenzofurazan-4-yl)amine | 4-(4-morpholinyl)-2,1,3-benzoxadiazol-7-amine | 4-morpholin-4-yl-2,1,3-benzoxadiazol-7-amine | MLS000764893 | SMR000290498 | cid_1095027 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12N4O2 |
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| Mol. Mass. | 220.2279 |
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| SMILES | Nc1ccc(N2CCOCC2)c2nonc12 |
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| Structure | 
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