| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM83941 |
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| Substrate/Competitor | n/a |
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| IC50 | 2080±434 nM |
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| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM83941 |
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| n/a |
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| Name | BDBM83941 |
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| Synonyms: | 6-methyl-8H-pyrimido[5,4-e][1,2,4]triazine-5,7-dione | 6-methyl-8H-pyrimido[5,4-e][1,2,4]triazine-5,7-quinone | MLS001048964 | SMR000008544 | cid_5351216 |
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| Type | Small organic molecule |
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| Emp. Form. | C6H5N5O2 |
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| Mol. Mass. | 179.1362 |
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| SMILES | Cn1c(=O)[nH]c2nncnc2c1=O |
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| Structure | 
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