| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM93611 |
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| Substrate/Competitor | n/a |
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| IC50 | 2350±263 nM |
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| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM93611 |
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| n/a |
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| Name | BDBM93611 |
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| Synonyms: | (4-chloro-3-nitro-phenyl)-[(5-nitro-2-thienyl)methylene]amine | 4-chloro-3-nitro-N-[(5-nitro-2-thienyl)methylene]aniline | MLS000702279 | N-(4-chloranyl-3-nitro-phenyl)-1-(5-nitrothiophen-2-yl)methanimine | N-(4-chloro-3-nitrophenyl)-1-(5-nitro-2-thiophenyl)methanimine | N-(4-chloro-3-nitrophenyl)-1-(5-nitrothiophen-2-yl)methanimine | SMR000228570 | cid_628390 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H6ClN3O4S |
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| Mol. Mass. | 311.701 |
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| SMILES | [O-][N+](=O)c1ccc(\C=N\c2ccc(Cl)c(c2)[N+]([O-])=O)s1 |
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| Structure | 
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