| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM83904 |
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| Substrate/Competitor | n/a |
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| IC50 | 384±43 nM |
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| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM83904 |
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| n/a |
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| Name | BDBM83904 |
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| Synonyms: | 4-tert-Butyl-benzoic acid N'-(2,6-di-piperidin-1-yl-pyrimidin-4-yl)-hydrazide | 4-tert-butyl-N'-(2,6-dipiperidinopyrimidin-4-yl)benzohydrazide | 4-tert-butyl-N'-[2,6-di(piperidin-1-yl)pyrimidin-4-yl]benzohydrazide | MLS000563386 | N'-[2,6-bis(1-piperidinyl)-4-pyrimidinyl]-4-tert-butylbenzohydrazide | SMR000176235 | cid_3121367 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H36N6O |
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| Mol. Mass. | 436.5929 |
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| SMILES | CC(C)(C)c1ccc(cc1)C(=O)NNc1cc(nc(n1)N1CCCCC1)N1CCCCC1 |
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| Structure | 
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