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TargetSentrin-specific protease 8
LigandBDBM38837
Substrate/Competitorn/a
IC50 148±23 nM
Citation PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article
 
Sentrin-specific protease 8
Name:Sentrin-specific protease 8
Synonyms:DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:Enzyme Catalytic Domain
Mol. Mass.:24104.52
Organism:Homo sapiens (Human)
Description:gi_262118306
Residue:212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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  Blast E-value cutoff:
BDBM38837
n/a
NameBDBM38837
Synonyms:2-(2-phenylethyl)-4H-isoquinoline-1,3-dione | 2-phenethyl-4H-isoquinoline-1,3-quinone | MLS000119149 | SMR000096084 | cid_713096
TypeSmall organic molecule
Emp. Form.C17H15NO2
Mol. Mass.265.3065
SMILESO=C1Cc2ccccc2C(=O)N1CCc1ccccc1
Structure
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