| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
|---|
| Ligand | BDBM83993 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 2680±285 nM |
|---|
| Citation |  PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Sentrin-specific protease 8 |
|---|
| Name: | Sentrin-specific protease 8 |
|---|
| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 24104.52 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_262118306 |
|---|
| Residue: | 212 |
|---|
| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
|
|
|
|---|
| BDBM83993 |
|---|
| n/a |
|---|
| Name | BDBM83993 |
|---|
| Synonyms: | 6-(2-morpholin-4-ylethylamino)quinolin-8-ol;2,2,2-trifluoroacetic acid | 6-(2-morpholin-4-ylethylamino)quinolin-8-ol;2,2,2-tris(fluoranyl)ethanoic acid | 6-(2-morpholinoethylamino)quinolin-8-ol;2,2,2-trifluoroacetic acid | 6-[2-(4-morpholinyl)ethylamino]-8-quinolinol;2,2,2-trifluoroacetic acid | MLS002391564 | SMR001355532 | cid_44143222 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H19N3O2 |
|---|
| Mol. Mass. | 273.3303 |
|---|
| SMILES | Oc1cc(NCCN2CCOCC2)cc2cccnc12 |
|---|
| Structure | 
|
|---|
Search and Browse
