Reaction Details |
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Target | Sentrin-specific protease 8 |
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Ligand | BDBM71372 |
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Substrate/Competitor | n/a |
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IC50 | 401±74 nM |
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Citation | PubChem, PC Dose-response confirmation of uHTS inhibitor hits of Sentrin-Specific Protease 8 using a kinetic assay with Nedd8 Protein Substrate PubChem Bioassay(2012)[AID] |
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More Info.: | Get all data from this article |
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Sentrin-specific protease 8 |
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Name: | Sentrin-specific protease 8 |
Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 24104.52 |
Organism: | Homo sapiens (Human) |
Description: | gi_262118306 |
Residue: | 212 |
Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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BDBM71372 |
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n/a |
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Name | BDBM71372 |
Synonyms: | 2-(4-methoxybenzyl)-1,3(2H,4H)-isoquinolinedione | 2-[(4-methoxyphenyl)methyl]-4H-isoquinoline-1,3-dione | 2-p-anisyl-4H-isoquinoline-1,3-quinone | MLS001165242 | SMR000549780 | cid_1475552 |
Type | Small organic molecule |
Emp. Form. | C17H15NO3 |
Mol. Mass. | 281.3059 |
SMILES | COc1ccc(CN2C(=O)Cc3ccccc3C2=O)cc1 |
Structure |
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