| Reaction Details |
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 | Report a problem with these data |
| Target | Protein Wnt-3a |
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| Ligand | BDBM35354 |
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| Substrate/Competitor | n/a |
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| IC50 | 1430±n/a nM |
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| Citation |  PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Protein Wnt-3a |
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| Name: | Protein Wnt-3a |
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| Synonyms: | WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39269.29 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_813156 |
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| Residue: | 352 |
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| Sequence: | MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYV
EIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGV
AFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDAR
SAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASE
MVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVS
SHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
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| BDBM35354 |
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| n/a |
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| Name | BDBM35354 |
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| Synonyms: | 4-N-(2-methylcyclohexyl)-1-N-(pyridin-4-ylmethyl)benzene-1,4-disulfonamide | Benzene-1,4-disulfonic acid 1-[(2-methyl-cyclohexyl)-amide] 4-[(pyridin-4-ylmethyl)-amide] | MLS000032786 | N'-(2-methylcyclohexyl)-N-(4-pyridylmethyl)benzene-1,4-disulfonamide | N4-(2-methylcyclohexyl)-N1-(pyridin-4-ylmethyl)benzene-1,4-disulfonamide | SMR000007163 | cid_645986 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H25N3O4S2 |
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| Mol. Mass. | 423.549 |
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| SMILES | CC1CCCCC1NS(=O)(=O)c1ccc(cc1)S(=O)(=O)NCc1ccncc1 |
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| Structure | 
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