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Reaction Details
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TargetHeat shock protein hsp-16.2
LigandBDBM93802
Substrate/Competitorn/a
IC50 47700±n/a nM
Citation PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay(2012)[AID]
More Info.:Get all data from this article
 
Heat shock protein hsp-16.2
Name:Heat shock protein hsp-16.2
Synonyms:HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:Enzyme Catalytic Domain
Mol. Mass.:16239.18
Organism:Caenorhabditis elegans
Description:gi_373219859
Residue:145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFK
PEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIE
APKKEAVQGRSIPIQQAIVEEKSAE
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BDBM93802
n/a
NameBDBM93802
Synonyms:MLS000680722 | N-[4-(2,4-difluorophenyl)-2-thiazolyl]carbamic acid ethyl ester | N-[4-(2,4-difluorophenyl)thiazol-2-yl]carbamic acid ethyl ester | SMR000272449 | cid_887761 | ethyl N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]carbamate | ethyl N-[4-[2,4-bis(fluoranyl)phenyl]-1,3-thiazol-2-yl]carbamate | ethyl [4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]carbamate
TypeSmall organic molecule
Emp. Form.C12H10F2N2O2S
Mol. Mass.284.282
SMILESCCOC(=O)Nc1nc(cs1)-c1ccc(F)cc1F
Structure
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