| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM90766 |
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| Substrate/Competitor | n/a |
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| IC50 | 5130±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM90766 |
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| n/a |
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| Name | BDBM90766 |
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| Synonyms: | 1-[(2-benzyl-5-tert-butyl-pyrazole-3-carbonyl)amino]-3-(3-chlorophenyl)urea | 1-[(2-benzyl-5-tert-butylpyrazole-3-carbonyl)amino]-3-(3-chlorophenyl)urea | 1-[[5-tert-butyl-2-(phenylmethyl)pyrazol-3-yl]carbonylamino]-3-(3-chlorophenyl)urea | 1-[[[5-tert-butyl-2-(phenylmethyl)-3-pyrazolyl]-oxomethyl]amino]-3-(3-chlorophenyl)urea | MLS000834880 | N1-(3-chlorophenyl)-2-{[1-benzyl-3-(tert-butyl)-1H-pyrazol-5-yl]carbonyl}hydrazine-1-carboxamide | SMR000461396 | cid_2744568 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H24ClN5O2 |
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| Mol. Mass. | 425.911 |
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| SMILES | CC(C)(C)c1cc(C(=O)NNC(=O)Nc2cccc(Cl)c2)n(Cc2ccccc2)n1 |
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| Structure | 
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