| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor-binding protein |
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| Ligand | BDBM65283 |
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| Substrate/Competitor | n/a |
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| IC50 | 5930±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor-binding protein |
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| Name: | Corticotropin-releasing factor-binding protein |
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| Synonyms: | CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36143.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P24387 |
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| Residue: | 322 |
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| Sequence: | MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRC
LDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKG
EKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNL
FPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGI
GDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQ
LEPYELENPNGNSIGEFCLSGL
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| BDBM65283 |
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| n/a |
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| Name | BDBM65283 |
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| Synonyms: | 4-({[(4-biphenylylcarbonyl)amino]carbonothioyl}amino)benzoic acid | 4-[(4-phenylbenzoyl)carbamothioylamino]benzoic acid | 4-[(4-phenylbenzoyl)thiocarbamoylamino]benzoic acid | 4-[(4-phenylphenyl)carbonylcarbamothioylamino]benzoic acid | 4-[[[[oxo-(4-phenylphenyl)methyl]amino]-sulfanylidenemethyl]amino]benzoic acid | MLS000676426 | SMR000298980 | cid_1017047 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H16N2O3S |
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| Mol. Mass. | 376.428 |
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| SMILES | OC(=O)c1ccc(NC(=S)NC(=O)c2ccc(cc2)-c2ccccc2)cc1 |
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| Structure | 
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