| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Ligand | BDBM51920 |
|---|
| Substrate/Competitor | n/a |
|---|
| EC50 | 4560±n/a nM |
|---|
| Citation |  PubChem, PC SAR analysis of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
|---|
| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 88079.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_47678551 |
|---|
| Residue: | 756 |
|---|
| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
|
|
|
|---|
| BDBM51920 |
|---|
| n/a |
|---|
| Name | BDBM51920 |
|---|
| Synonyms: | 4-(7-ethyl-1H-indol-3-yl)-N-(1-methoxypropan-2-yl)-1,3-thiazol-2-amine | 4-(7-ethyl-1H-indol-3-yl)-N-(1-methoxypropan-2-yl)-2-thiazolamine | MLS001176306 | SMR000591936 | [4-(7-ethyl-1H-indol-3-yl)thiazol-2-yl]-(2-methoxy-1-methyl-ethyl)amine | cid_16303496 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H21N3OS |
|---|
| Mol. Mass. | 315.433 |
|---|
| SMILES | CCc1cccc2c(c[nH]c12)-c1csc(NC(C)COC)n1 |
|---|
| Structure | 
|
|---|
Search and Browse
