| Reaction Details |
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 | Report a problem with these data |
| Target | Xylosyl- and glucuronyltransferase LARGE1 |
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| Ligand | BDBM67159 |
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| Substrate/Competitor | n/a |
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| EC50 | 6560±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of small molecule activators of alpha dystroglycan glycosylation PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| Xylosyl- and glucuronyltransferase LARGE1 |
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| Name: | Xylosyl- and glucuronyltransferase LARGE1 |
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| Synonyms: | KIAA0609 | LARG1_HUMAN | LARGE | LARGE1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 88079.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_47678551 |
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| Residue: | 756 |
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| Sequence: | MLGICRGRRKFLAASLSLLCIPAITWIYLFSGSFEDGKPVSLSPLESQAHSPRYTASSQR
ERESLEVRMREVEEENRALRRQLSLAQGRAPSHRRGNHSKTYSMEEGTGDSENLRAGIVA
GNSSECGQQPVVEKCETIHVAIVCAGYNASRDVVTLVKSVLFHRRNPLHFHLIADSIAEQ
ILATLFQTWMVPAVRVDFYNADELKSEVSWIPNKHYSGIYGLMKLVLTKTLPANLERVIV
LDTDITFATDIAELWAVFHKFKGQQVLGLVENQSDWYLGNLWKNHRPWPALGRGYNTGVI
LLLLDKLRKMKWEQMWRLTAERELMGMLSTSLADQDIFNAVIKQNPFLVYQLPCFWNVQL
SDHTRSEQCYRDVSDLKVIHWNSPKKLRVKNKHVEFFRNLYLTFLEYDGNLLRRELFGCP
SEADVNSENLQKQLSELDEDDLCYEFRRERFTVHRTHLYFLHYEYEPAADSTDVTLVAQL
SMDRLQMLEAICKHWEGPISLALYLSDAEAQQFLRYAQGSEVLMSRHNVGYHIVYKEGQF
YPVNLLRNVAMKHISTPYMFLSDIDFLPMYGLYEYLRKSVIQLDLANTKKAMIVPAFETL
RYRLSFPKSKAELLSMLDMGTLFTFRYHVWTKGHAPTNFAKWRTATTPYRVEWEADFEPY
VVVRRDCPEYDRRFVGFGWNKVAHIMELDVQEYEFIVLPNAYMIHMPHAPSFDITKFRSN
KQYRICLKTLKEEFQQDMSRRYGFAALKYLTAENNS
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| BDBM67159 |
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| n/a |
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| Name | BDBM67159 |
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| Synonyms: | 2-(2,3-diketoindolin-1-yl)acetic acid isopropyl ester | 2-(2,3-dioxo-1-indolyl)acetic acid propan-2-yl ester | MLS000550130 | SMR000115784 | cid_4328866 | isopropyl (2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetate | propan-2-yl 2-(2,3-dioxoindol-1-yl)acetate | propan-2-yl 2-[2,3-bis(oxidanylidene)indol-1-yl]ethanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C13H13NO4 |
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| Mol. Mass. | 247.2466 |
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| SMILES | CC(C)OC(=O)CN1C(=O)C(=O)c2ccccc12 |
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| Structure | 
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