| Reaction Details |
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 | Report a problem with these data |
| Target | ADP-ribosylation factor GTPase-activating protein 1 |
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| Ligand | BDBM95224 |
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| Substrate/Competitor | n/a |
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| IC50 | 34293±n/a nM |
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| Citation |  PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay(2012)[AID] |
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| More Info.: | Get all data from this article |
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| ADP-ribosylation factor GTPase-activating protein 1 |
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| Name: | ADP-ribosylation factor GTPase-activating protein 1 |
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| Synonyms: | ARFG1_RAT | Arf1gap | Arfgap1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 45436.38 |
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| Organism: | Rattus norvegicus |
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| Description: | gi_21489979 |
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| Residue: | 415 |
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| Sequence: | MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVR
SVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAE
GKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQE
NRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKA
SELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAED
TSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSS
DSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
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| BDBM95224 |
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| n/a |
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| Name | BDBM95224 |
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| Synonyms: | MLS001146387 | N-[(E)-[3-(4-bromobenzyl)-4-chloro-2-keto-4-thiazolin-5-yl]methyleneamino]-2-furamide | N-[(E)-[3-[(4-bromophenyl)methyl]-4-chloranyl-2-oxidanylidene-1,3-thiazol-5-yl]methylideneamino]furan-2-carboxamide | N-[(E)-[3-[(4-bromophenyl)methyl]-4-chloro-2-oxo-1,3-thiazol-5-yl]methylideneamino]furan-2-carboxamide | N-[(E)-[3-[(4-bromophenyl)methyl]-4-chloro-2-oxo-5-thiazolyl]methylideneamino]-2-furancarboxamide | SMR000646826 | cid_6880175 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H11BrClN3O3S |
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| Mol. Mass. | 440.699 |
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| SMILES | Clc1c(\C=N\NC(=O)c2ccco2)sc(=O)n1Cc1ccc(Br)cc1 |
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| Structure | 
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