| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Envelope glycoprotein gp160 |
|---|
| Ligand | BDBM48988 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 16348±n/a nM |
|---|
| Citation |  PubChem, PC TRFRET-based biochemical high throughput dose response assay for small molecules that bind to the HIV-1-gp120 binding antibody, PG9 PubChem Bioassay(2012)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Envelope glycoprotein gp160 |
|---|
| Name: | Envelope glycoprotein gp160 |
|---|
| Synonyms: | ENV_HV1H2 | Envelope polyprotein GP160 | Envelope surface glycoprotein gp160, precursor | HIV-1 B HXB2-LAI-IIIB-BRU | env |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 97241.93 |
|---|
| Organism: | Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) |
|---|
| Description: | n/a |
|---|
| Residue: | 856 |
|---|
| Sequence: | MRVKEKYQHLWRWGWRWGTMLLGMLMICSATEKLWVTVYYGVPVWKEATTTLFCASDAKA
YDTEVHNVWATHACVPTDPNPQEVVLVNVTENFNMWKNDMVEQMHEDIISLWDQSLKPCV
KLTPLCVSLKCTDLKNDTNTNSSSGRMIMEKGEIKNCSFNISTSIRGKVQKEYAFFYKLD
IIPIDNDTTSYKLTSCNTSVITQACPKVSFEPIPIHYCAPAGFAILKCNNKTFNGTGPCT
NVSTVQCTHGIRPVVSTQLLLNGSLAEEEVVIRSVNFTDNAKTIIVQLNTSVEINCTRPN
NNTRKRIRIQRGPGRAFVTIGKIGNMRQAHCNISRAKWNNTLKQIASKLREQFGNNKTII
FKQSSGGDPEIVTHSFNCGGEFFYCNSTQLFNSTWFNSTWSTEGSNNTEGSDTITLPCRI
KQIINMWQKVGKAMYAPPISGQIRCSSNITGLLLTRDGGNSNNESEIFRPGGGDMRDNWR
SELYKYKVVKIEPLGVAPTKAKRRVVQREKRAVGIGALFLGFLGAAGSTMGAASMTLTVQ
ARQLLSGIVQQQNNLLRAIEAQQHLLQLTVWGIKQLQARILAVERYLKDQQLLGIWGCSG
KLICTTAVPWNASWSNKSLEQIWNHTTWMEWDREINNYTSLIHSLIEESQNQQEKNEQEL
LELDKWASLWNWFNITNWLWYIKLFIMIVGGLVGLRIVFAVLSIVNRVRQGYSPLSFQTH
LPTPRGPDRPEGIEEEGGERDRDRSIRLVNGSLALIWDDLRSLCLFSYHRLRDLLLIVTR
IVELLGRRGWEALKYWWNLLQYWSQELKNSAVSLLNATAIAVAEGTDRVIEVVQGACRAI
RHIPRRIRQGLERILL
|
|
|
|---|
| BDBM48988 |
|---|
| n/a |
|---|
| Name | BDBM48988 |
|---|
| Synonyms: | 8-[(1-Cyclopentyl-1H-tetrazol-5-yl)-thiomorpholin-4-yl-methyl]-2,3-dihydro-6H-[1,4]dioxino[2,3-g]quinolin-7-one | 8-[(1-cyclopentyl-1,2,3,4-tetrazol-5-yl)-thiomorpholin-4-yl-methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one | 8-[(1-cyclopentyl-5-tetrazolyl)-thiomorpholin-4-ylmethyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one | 8-[(1-cyclopentyltetrazol-5-yl)-thiomorpholin-4-ylmethyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one | 8-[(1-cyclopentyltetrazol-5-yl)-thiomorpholino-methyl]-3,6-dihydro-2H-[1,4]dioxino[2,3-g]quinolin-7-one | MLS000074840 | SMR000002968 | cid_645675 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26N6O3S |
|---|
| Mol. Mass. | 454.545 |
|---|
| SMILES | O=c1[nH]c2cc3OCCOc3cc2cc1C(N1CCSCC1)c1nnnn1C1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
