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TargetTumor necrosis factor receptor superfamily member 10B
LigandBDBM53017
Substrate/Competitorn/a
EC50>12500±n/a nM
Citation PubChem, PC Dose Response confirmation of uHTS hits for a small molecule Caspase-8 TRAIL sensitizers in a luminescence panel assay PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article
 
Tumor necrosis factor receptor superfamily member 10B
Name:Tumor necrosis factor receptor superfamily member 10B
Synonyms:DR5 | KILLER | TNFRSF10B | TR10B_HUMAN | TRAILR2 | TRICK2 | ZTNFR9 | tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens]
Type:Enzyme Catalytic Domain
Mol. Mass.:47869.76
Organism:Homo sapiens (Human)
Description:gi_224494019
Residue:440
Sequence:
MEQRGQNAPAASGARKRHGPGPREARGARPGPRVPKTLVLVVAAVLLLVSAESALITQQD
LAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCD
SGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVH
KESGTKHSGEVPAVEETVTSSPGTPASPCSLSGIIIGVTVAAVVLIVAVFVCKSLLWKKV
LPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQEPAEPTGV
NMLSPGESEHLLEPAEAERSQRRRLLVPANEGDPTETLRQCFDDFADLVPFDSWEPLMRK
LGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLGERLAKQKIED
HLLSSGKFMYLEGNADSAMS
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BDBM53017
n/a
NameBDBM53017
Synonyms:(8-amino-7-methyl-phenazin-2-yl)-dimethyl-amine | 8-N,8-N,3-trimethylphenazine-2,8-diamine | MLS001179138 | N-(8-amino-7-methyl-2-phenazinyl)-N,N-dimethylamine | N8,N8,3-trimethylphenazine-2,8-diamine | SMR000476020 | cid_11106
TypeSmall organic molecule
Emp. Form.C15H16N4
Mol. Mass.252.3143
SMILESCN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1
Structure
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