BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetLow molecular weight phosphotyrosine protein phosphatase
LigandBDBM50225
Substrate/Competitorn/a
IC50>80000±n/a nM
Citation PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay PubChem Bioassay(2013)[AID]
More Info.:Get all data from this article
 
Low molecular weight phosphotyrosine protein phosphatase
Name:Low molecular weight phosphotyrosine protein phosphatase
Synonyms:3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:n/a
Mol. Mass.:18042.81
Organism:Homo sapiens (Human)
Description:P24666
Residue:158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50225
n/a
NameBDBM50225
Synonyms:1-(4-Chloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]thiadiazol-2-yl)-urea | 1-(4-chlorophenyl)-3-(5-pyridin-4-yl-1,3,4-thiadiazol-2-yl)urea | 1-(4-chlorophenyl)-3-[5-(4-pyridyl)-1,3,4-thiadiazol-2-yl]urea | CHEMBL1488371 | MLS000559246 | SMR000178208 | cid_931186
TypeSmall organic molecule
Emp. Form.C14H10ClN5OS
Mol. Mass.331.78
SMILESClc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: