| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 22 |
|---|
| Ligand | BDBM94928 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | >80000±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in a fluorescence-based, Lymphoid Phosphatase (PTPN22, LYP-1) selectivity Assay PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Tyrosine-protein phosphatase non-receptor type 22 |
|---|
| Name: | Tyrosine-protein phosphatase non-receptor type 22 |
|---|
| Synonyms: | 3.1.3.48 | Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP | LyP | Lymphoid phosphatase | Lymphoid phosphatase (Lyp) | PEP | PEST-domain phosphatase | PTN22_HUMAN | PTPN22 | PTPN8 | Tyrosine-protein phosphatase non-receptor type 22 (LYP) | tyrosine-protein phosphatase non-receptor type 22 isoform 1 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 91712.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9Y2R2 |
|---|
| Residue: | 807 |
|---|
| Sequence: | MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY
KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY
SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS
ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI
DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK
HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE
ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL
LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC
FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW
PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES
AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS
EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET
YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS
SSFLNFGFANRFSKPKGPRNPPPTWNI
|
|
|
|---|
| BDBM94928 |
|---|
| n/a |
|---|
| Name | BDBM94928 |
|---|
| Synonyms: | (2E)-2-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-3-bicyclo[2.2.1]hept-5-en-2-ylacrylonitrile | (E)-2-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-3-(5-bicyclo[2.2.1]hept-2-enyl)-2-propenenitrile | (E)-2-[4-amino-6-(dimethylamino)-1,3,5-triazin-2-yl]-3-(5-bicyclo[2.2.1]hept-2-enyl)prop-2-enenitrile | (E)-2-[4-amino-6-(dimethylamino)-s-triazin-2-yl]-3-(5-bicyclo[2.2.1]hept-2-enyl)acrylonitrile | (E)-2-[4-azanyl-6-(dimethylamino)-1,3,5-triazin-2-yl]-3-(5-bicyclo[2.2.1]hept-2-enyl)prop-2-enenitrile | MLS000086000 | SMR000021329 | cid_5293405 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H18N6 |
|---|
| Mol. Mass. | 282.3436 |
|---|
| SMILES | [H]C12CC(\C=C(/C#N)c3nc(N)nc(n3)N(C)C)C([H])(C1)C=C2 |c:23,THB:4:3:20:21.22| |
|---|
| Structure | 
|
|---|
Search and Browse
