| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 22 |
|---|
| Ligand | BDBM94890 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | 42200±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in a fluorescence-based, Lymphoid Phosphatase (PTPN22, LYP-1) selectivity Assay PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Tyrosine-protein phosphatase non-receptor type 22 |
|---|
| Name: | Tyrosine-protein phosphatase non-receptor type 22 |
|---|
| Synonyms: | 3.1.3.48 | Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP | LyP | Lymphoid phosphatase | Lymphoid phosphatase (Lyp) | PEP | PEST-domain phosphatase | PTN22_HUMAN | PTPN22 | PTPN8 | Tyrosine-protein phosphatase non-receptor type 22 (LYP) | tyrosine-protein phosphatase non-receptor type 22 isoform 1 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 91712.31 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9Y2R2 |
|---|
| Residue: | 807 |
|---|
| Sequence: | MDQREILQKFLDEAQSKKITKEEFANEFLKLKRQSTKYKADKTYPTTVAEKPKNIKKNRY
KDILPYDYSRVELSLITSDEDSSYINANFIKGVYGPKAYIATQGPLSTTLLDFWRMIWEY
SVLIIVMACMEYEMGKKKCERYWAEPGEMQLEFGPFSVSCEAEKRKSDYIIRTLKVKFNS
ETRTIYQFHYKNWPDHDVPSSIDPILELIWDVRCYQEDDSVPICIHCSAGCGRTGVICAI
DYTWMLLKDGIIPENFSVFSLIREMRTQRPSLVQTQEQYELVYNAVLELFKRQMDVIRDK
HSGTESQAKHCIPEKNHTLQADSYSPNLPKSTTKAAKMMNQQRTKMEIKESSSFDFRTSE
ISAKEELVLHPAKSSTSFDFLELNYSFDKNADTTMKWQTKAFPIVGEPLQKHQSLDLGSL
LFEGCSNSKPVNAAGRYFNSKVPITRTKSTPFELIQQRETKEVDSKENFSYLESQPHDSC
FVEMQAQKVMHVSSAELNYSLPYDSKHQIRNASNVKHHDSSALGVYSYIPLVENPYFSSW
PPSGTSSKMSLDLPEKQDGTVFPSSLLPTSSTSLFSYYNSHDSLSLNSPTNISSLLNQES
AVLATAPRIDDEIPPPLPVRTPESFIVVEEAGEFSPNVPKSLSSAVKVKIGTSLEWGGTS
EPKKFDDSVILRPSKSVKLRSPKSELHQDRSSPPPPLPERTLESFFLADEDCMQAQSIET
YSTSYPDTMENSTSSKQTLKTPGKSFTRSKSLKILRNMKKSICNSCPPNKPAESVQSNNS
SSFLNFGFANRFSKPKGPRNPPPTWNI
|
|
|
|---|
| BDBM94890 |
|---|
| n/a |
|---|
| Name | BDBM94890 |
|---|
| Synonyms: | 1,3-Dimethyl-5,6-dinitro-2-[3-(1,3,3-trimethyl-1,3-dihydro-indol-2-ylidene)-propenyl]-3H-benzoimidazol-1-ium | 1,3-dimethyl-5,6-dinitro-2-[(E,3E)-3-(1,3,3-trimethyl-2-indolylidene)prop-1-enyl]benzimidazol-3-ium;4-methylbenzenesulfonate | 1,3-dimethyl-5,6-dinitro-2-[(E,3E)-3-(1,3,3-trimethylindol-2-ylidene)prop-1-enyl]benzimidazol-3-ium;4-methylbenzenesulfonate | 1,3-dimethyl-5,6-dinitro-2-[(E,3E)-3-(1,3,3-trimethylindolin-2-ylidene)prop-1-enyl]benzimidazol-3-ium;tosylate | MLS001210139 | SMR000505098 | cid_56603498 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H24N5O4 |
|---|
| Mol. Mass. | 434.4672 |
|---|
| SMILES | CN1\C(=C\C=C\c2n(C)c3cc(c(cc3[n+]2C)[N+]([O-])=O)[N+]([O-])=O)C(C)(C)c2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
