Ki Summary

Reaction Details

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Target

Trace amine-associated receptor 1

Ligand

BDBM96868

Substrate/Competitor

n/a

IC50

3721±n/a nM

Citation

PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay(2013)[AID]

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Trace amine-associated receptor 1

Name:

Trace amine-associated receptor 1

Synonyms:

Type:

PROTEIN

Mol. Mass.:

39107.47

Organism:

Homo sapiens (Human)

Description:

ChEMBL_792734

Residue:

339

Sequence:

MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW
LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID
RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRG
GCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNG
ISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFN
PMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS

BDBM96868

n/a

Name

BDBM96868

Synonyms:

(2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-(cyclopentanecarbonylamino)-3-(3-pyridyl)propanoyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-(cyclopentanecarbonylamino)-3-pyridin-3-ylpropanoyl]pyrrolidine-2-carboxamide;2,2,2-trifluoroacetic acid | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-(cyclopentylcarbonylamino)-3-pyridin-3-yl-propanoyl]pyrrolidine-2-carboxamide;2,2,2-tris(fluoranyl)ethanoic acid | (2S)-N-[2-(2-chlorophenyl)ethyl]-1-[(2S)-2-[[cyclopentyl(oxo)methyl]amino]-1-oxo-3-(3-pyridinyl)propyl]-2-pyrrolidinecarboxamide;2,2,2-trifluoroacetic acid | MLS003777888 | SMR002440868 | cid_53361885

Type

Small organic molecule

Emp. Form.

C27H33ClN4O3

Mol. Mass.

497.029

SMILES

Clc1ccccc1CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cccnc1)NC(=O)C1CCCC1

Structure