| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nuclear receptor subfamily 0 group B member 1 |
|---|
| Ligand | BDBM91138 |
|---|
| Substrate/Competitor | n/a |
|---|
| IC50 | >2499±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay(2013)[AID] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Nuclear receptor subfamily 0 group B member 1 |
|---|
| Name: | Nuclear receptor subfamily 0 group B member 1 |
|---|
| Synonyms: | AHC | DAX1 | NR0B1 | NR0B1_HUMAN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 51729.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_5016090 |
|---|
| Residue: | 470 |
|---|
| Sequence: | MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNV
ALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGL
PGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQR
PGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSS
GALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELA
QDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQA
IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQ
GPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
|
|
|
|---|
| BDBM91138 |
|---|
| n/a |
|---|
| Name | BDBM91138 |
|---|
| Synonyms: | MLS001240093 | N-(3-aminocarbonyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-1-methyl-pyrazole-3-carboxamide | N-(3-carbamoyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-1-methyl-3-pyrazolecarboxamide | N-(3-carbamoyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-1-methyl-pyrazole-3-carboxamide | N-(3-carbamoyl-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-1-methylpyrazole-3-carboxamide | N-[3-(aminocarbonyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl]-1-methyl-1H-pyrazole-3-carboxamide | SMR000673292 | cid_1222859 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H18N4O2S |
|---|
| Mol. Mass. | 318.394 |
|---|
| SMILES | Cn1ccc(n1)C(=O)Nc1sc2CCCCCc2c1C(N)=O |
|---|
| Structure | 
|
|---|
Search and Browse
