| Reaction Details |
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 | Report a problem with these data |
| Target | Nuclear receptor subfamily 0 group B member 1 |
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| Ligand | BDBM50014875 |
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| Substrate/Competitor | n/a |
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| IC50 | 212.03±n/a nM |
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| Citation |  PubChem, PC Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1 PubChem Bioassay(2013)[AID] |
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| More Info.: | Get all data from this article |
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| Nuclear receptor subfamily 0 group B member 1 |
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| Name: | Nuclear receptor subfamily 0 group B member 1 |
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| Synonyms: | AHC | DAX1 | NR0B1 | NR0B1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51729.22 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5016090 |
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| Residue: | 470 |
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| Sequence: | MAGENHQWQGSILYNMLMSAKQTRAAPEAPETRLVDQCWGCSCGDEPGVGREGLLGGRNV
ALLYRCCFCGKDHPRQGSILYSMLTSAKQTYAAPKAPEATLGPCWGCSCGSDPGVGRAGL
PGGRPVALLYRCCFCGEDHPRQGSILYSLLTSSKQTHVAPAAPEARPGGAWWDRSYFAQR
PGGKEALPGGRATALLYRCCFCGEDHPQQGSTLYCVPTSTNQAQAAPEERPRAPWWDTSS
GALRPVALKSPQVVCEAASAGLLKTLRFVKYLPCFQVLPLDQQLVLVRNCWASLLMLELA
QDRLQFETVEVSEPSMLQKILTTRRRETGGNEPLPVPTLQHHLAPPAEARKVPSASQVQA
IKCFLSKCWSLNISTKEYAYLKGTVLFNPDVPGLQCVKYIQGLQWGTQQILSEHTRMTHQ
GPHDRFIELNSTLFLLRFINANVIAELFFRPIIGTVSMDDMMLEMLCTKI
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| BDBM50014875 |
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| n/a |
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| Name | BDBM50014875 |
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| Synonyms: | (S)-7-Amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one | 7-Amino-1,2,3-trimethoxy-10-methylsulfanyl-6,7-dihydro-5H-benzo[a]heptalen-9-one | CHEMBL298240 | N-deacetylthiocolchicine | cid_426728 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23NO4S |
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| Mol. Mass. | 373.466 |
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| SMILES | COc1cc2CC[C@H](N)c3cc(=O)c(SC)ccc3-c2c(OC)c1OC |r| |
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| Structure | 
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