Reaction Details |
![](/images/Email.png) | Report a problem with these data |
Target | Glutaminyl-peptide cyclotransferase |
---|
Ligand | BDBM102924 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Spectrophotometric Assay |
---|
Ki | 228±n/a nM |
---|
IC50 | 3.71e+3±n/a nM |
---|
Citation | Heiser, U; Ramsbeck, D; Hoffmann, T; Boehme, L Inhibitors US Patent US8541596 Publication Date 9/24/2013 |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Glutaminyl-peptide cyclotransferase |
---|
Name: | Glutaminyl-peptide cyclotransferase |
Synonyms: | Glutaminyl Cyclase | Glutaminyl cyclase (QC) | Glutaminyl-peptide cyclotransferase | Glutaminyl-peptide cyclotransferase precursor (QC) | Glutaminyl-tRNA cyclotransferase | Glutamyl cyclase (QC) | QPCT | QPCT_HUMAN |
Type: | Enzyme |
Mol. Mass.: | 40877.05 |
Organism: | Homo sapiens (Human) |
Description: | Q16769 |
Residue: | 361 |
Sequence: | MAGGRHRRVVGTLHLLLLVAALPWASRGVSPSASAWPEEKNYHQPAILNSSALRQIAEGT
SISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSF
SNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLS
LKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHG
MDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYG
GVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLH
L
|
|
|
BDBM102924 |
---|
n/a |
---|
Name | BDBM102924 |
Synonyms: | US8541596, 55 |
Type | Small organic molecule |
Emp. Form. | C23H23N3OS |
Mol. Mass. | 389.513 |
SMILES | COc1cccc(CN(Cc2ccc(SC)cc2)c2ccc3nc[nH]c3c2)c1 |
Structure |
|