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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine/threonine-protein kinase pim-1 | ||
| Ligand | BDBM106923 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ATP Depletion Assay | ||
| pH | 7.5±0 | ||
| IC50 | 1±n/a nM | ||
| Citation |  Burger, MT; Han, W; Lan, J; Nishiguchi, G Kinase inhibitors and methods of their use US Patent US8592455 Publication Date 11/26/2013 | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Serine/threonine-protein kinase pim-1 | |||
| Name: | Serine/threonine-protein kinase pim-1 | ||
| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) | ||
| Type: | Protein | ||
| Mol. Mass.: | 35681.82 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P11309 | ||
| Residue: | 313 | ||
| Sequence: |
| ||
| BDBM106923 | |||
| n/a | |||
| Name | BDBM106923 | ||
| Synonyms: | US8592455, 123 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H27F3N4O2 | ||
| Mol. Mass. | 484.5134 | ||
| SMILES | COc1cc(F)c(c(F)c1)-c1nc(ccc1F)C(=O)Nc1cnccc1[C@H]1C[C@@H](N)CC(C)(C)C1 |r,wU:26.28,28.31,(2,6.16,;3.33,5.39,;3.33,3.85,;4.67,3.08,;4.67,1.54,;6,.77,;3.33,.77,;2,1.54,;.67,.77,;2,3.08,;3.33,-.77,;2,-1.54,;2,-3.08,;3.33,-3.85,;4.67,-3.08,;4.67,-1.54,;6,-.77,;.67,-3.85,;.67,-5.39,;-.67,-3.08,;-2,-3.85,;-2,-5.39,;-3.33,-6.16,;-4.67,-5.39,;-4.67,-3.85,;-3.33,-3.08,;-3.33,-1.54,;-4.67,-.77,;-4.67,.77,;-6,1.54,;-3.33,1.54,;-2,.77,;-1,.77,;-1.23,2.1,;-2,-.77,)| | ||
| Structure | 
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