| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 9 |
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| Ligand | BDBM106957 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Assay |
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| pH | 7.5±0 |
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| Temperature | 303.15±0 K |
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| IC50 | 5.0e+2±n/a nM |
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| Citation |  Sheldrake, PW; Atrash, B; Green, S; McDonald, E; Frame, S Trisubstituted purine derivatives US Patent US8592581 Publication Date 11/26/2013 |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Cyclin-dependent kinase 9 |
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| Name: | Cyclin-dependent kinase 9 |
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| Synonyms: | C-2K | CDC2L4 | CDK9 | CDK9_HUMAN | Cell division cycle 2-like protein kinase 4 | Cell division protein kinase 9 | Cyclin-Dependent Kinase 9 (CDK9) | Cyclin-dependent kinase 9 (CDK9) | Serine/threonine-protein kinase PITALRE | TAK | Tat-associated kinase complex catalytic subunit |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 42789.13 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 372 |
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| Sequence: | MAKQYDSVECPFCDEVSKYEKLAKIGQGTFGEVFKARHRKTGQKVALKKVLMENEKEGFP
ITALREIKILQLLKHENVVNLIEICRTKASPYNRCKGSIYLVFDFCEHDLAGLLSNVLVK
FTLSEIKRVMQMLLNGLYYIHRNKILHRDMKAANVLITRDGVLKLADFGLARAFSLAKNS
QPNRYTNRVVTLWYRPPELLLGERDYGPPIDLWGAGCIMAEMWTRSPIMQGNTEQHQLAL
ISQLCGSITPEVWPNVDNYELYEKLELVKGQKRKVKDRLKAYVRDPYALDLIDKLLVLDP
AQRIDSDDALNHDFFWSDPMPSDLKGMLSTHLTSMFEYLAPPRRKGSQITQQSTNQSRNP
ATTNQTEFERVF
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| BDBM106957 |
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| n/a |
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| Name | BDBM106957 |
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| Synonyms: | US8592581, 8 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H28N6O |
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| Mol. Mass. | 332.4438 |
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| SMILES | CC[C@H](Nc1nc(NC2CCC2)c2ncn(C(C)C)c2n1)[C@@H](C)O |r| |
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| Structure | 
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