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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Carboxypeptidase B2 | ||
| Ligand | BDBM109249 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Enzyme Inhibition Assay | ||
| IC50 | 12±n/a nM | ||
| Citation |  Nagata, T; Inoue, M; Ashida, Y; Noguchi, K; Ono, M Cycloalkyl-substituted imidazole derivative US Patent US8609710 Publication Date 12/17/2013 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Carboxypeptidase B2 | |||
| Name: | Carboxypeptidase B2 | ||
| Synonyms: | CBPB2_HUMAN | CPB2 | CPU | Carboxypeptidase B2 | Carboxypeptidase B2 isoform A | Carboxypeptidase U | Plasma carboxypeptidase B | TAFI | Thrombin-activable fibrinolysis inhibitor | pCPB | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 48432.74 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q96IY4 | ||
| Residue: | 423 | ||
| Sequence: |
| ||
| BDBM109249 | |||
| n/a | |||
| Name | BDBM109249 | ||
| Synonyms: | US8609710, 13 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H29N3O2 | ||
| Mol. Mass. | 331.4525 | ||
| SMILES | NCCCC(Cc1cn(cn1)C1C2CC3CC(C2)CC1C3)C(O)=O |TLB:8:11:13:15.16.17,THB:15:14:11:18.16.17,15:16:11:13.14.20,18:19:13:15.16.17,18:16:13:11.20.19,(5.01,2.01,;3.68,1.24,;3.68,-.3,;2.34,-1.07,;2.34,-2.61,;1.01,-3.38,;-.32,-2.61,;-.32,-1.07,;-1.79,-.6,;-2.69,-1.84,;-1.79,-3.09,;-2.56,.74,;-4.05,.92,;-5.01,2.01,;-4.19,3.43,;-4.58,4.92,;-3.47,3.62,;-4.24,2.29,;-1.93,3.62,;-1.93,2.08,;-2.86,3.27,;3.68,-3.38,;3.68,-4.92,;5.01,-2.61,)| | ||
| Structure | 
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