Reaction Details | |||
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Target | Carboxypeptidase B2 | ||
Ligand | BDBM109255 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Enzyme Inhibition Assay | ||
IC50 | 21±n/a nM | ||
Citation | Nagata, T; Inoue, M; Ashida, Y; Noguchi, K; Ono, M Cycloalkyl-substituted imidazole derivative US Patent US8609710 Publication Date 12/17/2013 | ||
More Info.: | Get all data from this article, Assay Method | ||
Carboxypeptidase B2 | |||
Name: | Carboxypeptidase B2 | ||
Synonyms: | CBPB2_HUMAN | CPB2 | CPU | Carboxypeptidase B2 | Carboxypeptidase B2 isoform A | Carboxypeptidase U | Plasma carboxypeptidase B | TAFI | Thrombin-activable fibrinolysis inhibitor | pCPB | ||
Type: | Enzyme | ||
Mol. Mass.: | 48432.74 | ||
Organism: | Homo sapiens (Human) | ||
Description: | Q96IY4 | ||
Residue: | 423 | ||
Sequence: |
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BDBM109255 | |||
n/a | |||
Name | BDBM109255 | ||
Synonyms: | US8609710, 26 | ||
Type | Small organic molecule | ||
Emp. Form. | C17H28N4O2 | ||
Mol. Mass. | 320.4298 | ||
SMILES | C[C@H]1CC[C@@H](CC1)n1cnc(CC(N2CC[C@H](N)C2)C(O)=O)c1 |r,wU:4.7,wD:1.0,16.17,(-3.85,5.14,;-3.45,3.65,;-4.54,2.56,;-4.14,1.07,;-2.66,.68,;-1.57,1.76,;-1.97,3.25,;-2.26,-.81,;-3.16,-2.06,;-2.26,-3.3,;-.79,-2.83,;.54,-3.6,;1.87,-2.83,;1.87,-1.29,;.63,-.38,;1.1,1.08,;2.64,1.08,;3.41,2.42,;3.12,-.38,;3.21,-3.6,;4.54,-2.83,;3.21,-5.14,;-.79,-1.29,)| | ||
Structure |